Vardhman Health Point

• To facilitate cervical dilation during labor by relaxing the smooth muscles of the cervix and uterus

• Helps in shortening the first stage of labor

• Sometimes used to relieve spasms in the gastrointestinal or genitourinary tract

Primary Uses:

Methemoglobinemia (drug of choice)

• Converts methemoglobin (which cannot carry oxygen) back to hemoglobin

Ifosfamide-induced encephalopathy

• Used off-label as an antidote to neurotoxicity caused by the chemotherapy drug ifosfamide

Septic shock (vasoplegia)

• Occasionally used to counter vasodilatory shock unresponsive to vasopressors

Urinary tract visualization and surgical staining

• Used as a diagnostic dye

• Short-term treatment of acute decompensated heart failure

• Cardiogenic shock or low cardiac output after cardiac surgery

• Bridge to definitive therapy (e.g., transplant, mechanical circulatory support)

• Sometimes used in pediatric congenital heart disease surgery

Primary Uses:

Methemoglobinemia (drug of choice)

• Converts methemoglobin (which cannot carry oxygen) back to hemoglobin

Ifosfamide-induced encephalopathy

• Used off-label as an antidote to neurotoxicity caused by the chemotherapy drug ifosfamide

Septic shock (vasoplegia)

• Occasionally used to counter vasodilatory shock unresponsive to vasopressors

Urinary tract visualization and surgical staining

• Used as a diagnostic dye

Primary Uses:

Methemoglobinemia (drug of choice)

• Converts methemoglobin (which cannot carry oxygen) back to hemoglobin

Ifosfamide-induced encephalopathy

• Used off-label as an antidote to neurotoxicity caused by the chemotherapy drug ifosfamide

Septic shock (vasoplegia)

• Occasionally used to counter vasodilatory shock unresponsive to vasopressors

Urinary tract visualization and surgical staining

• Used as a diagnostic dye

Primary Uses:

Methemoglobinemia (drug of choice)

• Converts methemoglobin (which cannot carry oxygen) back to hemoglobin

Ifosfamide-induced encephalopathy

• Used off-label as an antidote to neurotoxicity caused by the chemotherapy drug ifosfamide

Septic shock (vasoplegia)

• Occasionally used to counter vasodilatory shock unresponsive to vasopressors

Urinary tract visualization and surgical staining

• Used as a diagnostic dye

• Treatment of severe or complicated malaria when oral therapy is not feasible

• Often used when rapid therapeutic levels are needed

• Sometimes used for babesiosis or other parasitic infections (less common)

• Quinine Dihydrochloride I.P. 300 mg.
• Water for Injection I.P. Q.S

• Acute angina pectoris and acute coronary syndrome (ACS)

• Acute decompensated heart failure with elevated left ventricular filling pressure

• Hypertensive emergencies

• Adjunct in perioperative hypertension

• Management of myocardial infarction to reduce cardiac workload